2172820-14-1
Chemical Structure
(S,R,S)-AHPC-PEG5-COOH
Synonym(s): VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58
- CAS No.: 2172820-14-1
- Formula:C36H54N4O11S
- Molecular Weight:750.90
IUPAC Name: (S)-21-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanoic acid
InChIKey: YDOJYEPMGKGKQV-ZLWRCJDJSA-N
SMILES: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3
Biological Activity: (S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].
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(S,R,S)-AHPC-PEG5-COOH | 99.79% | (S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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Keywords
