(S,R,S)-AHPC-Amide-PEG2-C2-NH2
Based on 1 Customer Validation
(S,R,S)-AHPC-Amide-PEG2-C2-NH2 is an E3 Ligase Ligand-Linker Conjugates that can be used to synthesize PROTAC PI3K/110β degrader-1 (HY-176421).
For research use only. We do not sell to patients.
- Purity: 97.16%
- CAS No.: 2138439-54-8
- Formula: C29H43N5O6S
- Molecular Weight:589.75
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2138439-54-8
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Appearance Solid
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Molecular Weight 589.75
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Formula C29H43N5O6S
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Color White to off-white
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SMILES
O=C(NCC1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(CCOCCOCCN)=O)C(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 125 mg/mL (211.95 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6956 mL | 8.4782 mL | 16.9563 mL | 42.3908 mL |
| 5 mM | 0.3391 mL | 1.6956 mL | 3.3913 mL | 8.4782 mL | |
| 10 mM | 0.1696 mL | 0.8478 mL | 1.6956 mL | 4.2391 mL | |
| 15 mM | 0.1130 mL | 0.5652 mL | 1.1304 mL | 2.8261 mL | |
| 20 mM | 0.0848 mL | 0.4239 mL | 0.8478 mL | 2.1195 mL | |
| 25 mM | 0.0678 mL | 0.3391 mL | 0.6783 mL | 1.6956 mL | |
| 30 mM | 0.0565 mL | 0.2826 mL | 0.5652 mL | 1.4130 mL | |
| 40 mM | 0.0424 mL | 0.2120 mL | 0.4239 mL | 1.0598 mL | |
| 50 mM | 0.0339 mL | 0.1696 mL | 0.3391 mL | 0.8478 mL | |
| 60 mM | 0.0283 mL | 0.1413 mL | 0.2826 mL | 0.7065 mL | |
| 80 mM | 0.0212 mL | 0.1060 mL | 0.2120 mL | 0.5299 mL | |
| 100 mM | 0.0170 mL | 0.0848 mL | 0.1696 mL | 0.4239 mL |