Muscle homing peptide M12
Based on 1 Customer Validation
Muscle homing peptide M12 is a muscle-homing peptide with high affinity for skeletal muscle and cardiac muscle. Muscle homing peptide M12 can mediate the targeted delivery of loaded drugs to skeletal muscle and cardiac muscle tissues.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 2896181-32-9
- Formula: C59H100N24O17
- Molecular Weight:1417.58
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Muscle homing peptide M12 binds to bioactive molecules or receptors on the surface of muscle cells, endowing liposomes with skeletal muscle-specific targeting ability and enabling the liposome system to accumulate specifically in skeletal muscle[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2896181-32-9
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Appearance Solid
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Molecular Weight 1417.58
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Formula C59H100N24O17
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Color White to off-white
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Sequence
Arg-Arg-Gln-Pro-Pro-Arg-Ser-Ile-Ser-Ser-His-Pro
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Sequence Shortening
RRQPPRSISSHP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (70.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 10 mg/mL (7.05 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Huang Z, et al. Muscle homing peptide modified liposomes loaded with EGCG improved skeletal muscle dysfunction by inhibiting inflammation in aging mice. Materials today. Bio. 2025 Dec;35:102265. [Content Brief]
[2]. Liu Y, et al. MCC950-Loaded M12-Liposome Nanoparticles for Targeted Inhibition of NLRP3 Inflammasome in Sepsis-Induced Muscle Atrophy. Journal of cachexia, sarcopenia and muscle. 2026 Apr;17(2):e70285. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.7054 mL | 3.5271 mL | 7.0543 mL | 17.6357 mL |
| 5 mM | 0.1411 mL | 0.7054 mL | 1.4109 mL | 3.5271 mL | |
| DMSO | 10 mM | 0.0705 mL | 0.3527 mL | 0.7054 mL | 1.7636 mL |
| 15 mM | 0.0470 mL | 0.2351 mL | 0.4703 mL | 1.1757 mL | |
| 20 mM | 0.0353 mL | 0.1764 mL | 0.3527 mL | 0.8818 mL | |
| 25 mM | 0.0282 mL | 0.1411 mL | 0.2822 mL | 0.7054 mL | |
| 30 mM | 0.0235 mL | 0.1176 mL | 0.2351 mL | 0.5879 mL | |
| 40 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4409 mL | |
| 50 mM | 0.0141 mL | 0.0705 mL | 0.1411 mL | 0.3527 mL | |
| 60 mM | 0.0118 mL | 0.0588 mL | 0.1176 mL | 0.2939 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Muscle homing peptide M12 Related Classifications
HY-P10646 Related Classifications
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- Muscle homing peptide M12
- 2896181-32-9
- Muscle homing peptide M 12
- Muscle homing peptide M-12
- Others
- D-galactose-induced aging mice
- Balb/c mice
- C2C12 myotubes
- age-related skeletal muscle dysfunction
- sepsis-induced myopathy
- C2C12 cells
- C2C12 murine myoblasts
- skeletal muscle
- cardiac muscle
- D-galactose-induced senescent C2C12 cells
- Inhibitor
- inhibitor
- inhibit