DPPE-PEG5000

DPPE-PEG5000 (2 mol./mol. total lipid) imparts colloidal stability to LipoParticles upon 20-fold dilution in PBS or cell culture medium and enables freeze-drying and rehydration without significant aggregation, while maintaining defined size, size distribution, and surface charge profiles^[1].
DPPE-PEG5000 (2 mol./mol. total lipid; 19.5-1250 μg/mL LipoParticles; 24 h) forms LipoParticles that are non-cytotoxic to human osteoblast MG63 cells at concentrations up to 1250 μg/mL after 24 h of incubation, with no reduction in cell metabolic activity^[1].
DPPE-PEG5000 (2 mol./mol. total lipid; 3,000 colloids per cell; 24 h) forms LipoParticles that are efficiently internalized into human osteoblast MG63 cells after 24 h of incubation at a dose of 3,000 colloids per cell, with localization in the cellular cytoplasm^[1].
DPPE-PEG5000 (2 mol./mol. total lipid; 22,000 colloids per cell; 24 h) forms LipoParticles that are internalized into human osteoblast MG63 cells after 24 h of incubation at a dose of 22,000 colloids per cell, with measurable fluorescence signals from both the PLGA core and lipid coating, and maintain high cell viability (89.7%)^[1].
DPPE-PEG5000 (2 mol./mol. total lipid; 22,000 colloids per infected cell; 24 h) forms LipoParticles that are internalized into Staphylococcus aureus-infected human osteoblast MG63 cells after 24 h of incubation at a dose of 22,000 colloids per cell, with localization near intracellular bacteria^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.