2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Alkyne-PEG5-SNAP

Alkyne-PEG5-SNAP  (Synonyms: Alkyne-PEG5-BG)

製品番号: HY-151646 純度: 98.95%
COA 取扱説明書 Technical Support

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Alkyne-PEG5-SNAP

Alkyne-PEG5-SNAP 構造式

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
5 mg $80 在庫あり
10 mg $125 在庫あり
25 mg $250 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Alkyne-PEG5-SNAP 関連抗体

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製品説明

Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation[1]. Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

分子量

556.61

分子式

C27H36N6O7
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC1=CC=C(COC2=C3N=CNC3=NC(N)=N2)C=C1)CCOCCOCCOCCOCCOCC#C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 125 mg/mL (224.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7966 mL 8.9830 mL 17.9659 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL
10 mM 0.1797 mL 0.8983 mL 1.7966 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.95%

COA (241 KB) HNMR (286 KB) LCMS (329 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7966 mL 8.9830 mL 17.9659 mL 44.9148 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL 8.9830 mL
10 mM 0.1797 mL 0.8983 mL 1.7966 mL 4.4915 mL
15 mM 0.1198 mL 0.5989 mL 1.1977 mL 2.9943 mL
20 mM 0.0898 mL 0.4491 mL 0.8983 mL 2.2457 mL
25 mM 0.0719 mL 0.3593 mL 0.7186 mL 1.7966 mL
30 mM 0.0599 mL 0.2994 mL 0.5989 mL 1.4972 mL
40 mM 0.0449 mL 0.2246 mL 0.4491 mL 1.1229 mL
50 mM 0.0359 mL 0.1797 mL 0.3593 mL 0.8983 mL
60 mM 0.0299 mL 0.1497 mL 0.2994 mL 0.7486 mL
80 mM 0.0225 mL 0.1123 mL 0.2246 mL 0.5614 mL
100 mM 0.0180 mL 0.0898 mL 0.1797 mL 0.4491 mL
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Alkyne-PEG5-SNAP Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alkyne-PEG5-SNAPAlkyne-PEG5-BGADC LinkerAntibody-drug conjugates linkerclick chemistry reagentalkynebenzylguanineSNAP-tagconjugationInhibitorinhibitorinhibit

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製品名:
Alkyne-PEG5-SNAP
製品番号:
HY-151646
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