1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. Lenalidomide-PEG1-azide

Lenalidomide-PEG1-azide 

Cat. No.: HY-133139 Purity: 95.70%
COA Handling Instructions

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136).

For research use only. We do not sell to patients.

Lenalidomide-PEG1-azide Chemical Structure

Lenalidomide-PEG1-azide Chemical Structure

CAS No. : 2185795-67-7

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100 mg USD 1200 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 (HY-133136)[1].

Molecular Weight

386.36

Formula

C17H18N6O5

CAS No.
SMILES

O=C(NC1=CC=CC2=C1CN(C(CC3)C(NC3=O)=O)C2=O)COCCN=[N+]=[N-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (258.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5883 mL 12.9413 mL 25.8826 mL
5 mM 0.5177 mL 2.5883 mL 5.1765 mL
10 mM 0.2588 mL 1.2941 mL 2.5883 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lenalidomide-PEG1-azide
Cat. No.:
HY-133139
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