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insulin-

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製品番号 Compare 製品名 Species Source Image
  • HY-P73243
    Insulin Protein, Human (P.pastoris)
    Maximum Cited Publications
    25 Publications Verification

    insulin; INS; IDDM; ILPR; IRDN; MODY10

    Human P. pastoris
    Insulin is an important hormone in glucose regulation, reducing blood glucose concentrations by increasing cellular permeability to simple sugars, amino acids, and fatty acids. Its multiple effects include accelerating glycolysis, promoting pentose phosphate cycle, and promoting hepatic glycogen synthesis. Insulin Protein, Human (P.pastoris) is the recombinant human-derived Insulin protein, expressed by P. pastoris, with tag free.
  • HY-P701240
    Insulin Protein, Bovine (P. pastoris)
    3 Publications Verification

    insulin; INS; IDDM; ILPR; IRDN; MODY10

    Bovine P. pastoris
    Insulin Protein regulates glucose metabolism in the body. It binds to insulin receptors, activating signaling pathways that facilitate glucose uptake and storage. Insulin Protein also regulates lipid metabolism and protein synthesis. Understanding its functions is crucial for developing treatments for diabetes and metabolic disorders. Insulin Protein, Bovine (P. pastoris) is the recombinant bovine-derived Insulin protein, expressed by P. pastoris, with tag free.
  • HY-P702540

    IDDM2; ILPR; insulin; IRDN; MODY10; Proinsulin

    Human E. coli
    Proinsulin is the precursor of insulin, a key hormone that regulates carbohydrate and lipid metabolism. Post-translational cleavage produces insulin, which consists of B and A chain peptides and a C peptide linked by disulfide bonds. Proinsulin Protein, Human (His) is the recombinant human-derived Proinsulin protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P73873A

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (HEK293, His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-10*His labeled tag.
  • HY-P73873

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (HEK293, His, solution) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P77515

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P73244

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human Sf9 insect cells
    The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (sf9, His-GST) is the recombinant human-derived Insulin R/CD220 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P705049

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Human HEK293
  • HY-P705177

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Cat HEK293
  • HY-P705295

    CD 220; HHF5; INSR; insulin R; insulin receptor; IR

    Dog HEK293
  • HY-P70176

    rHuinsulin-like 3/INSL3, His; insulin-like 3; Leydig insulin-like peptide; Relaxin-like factor; INSL3; RLF; RLNL

    Human HEK293
    Insulin-like 3/INSL3 Protein, Human (HEK293, His) is the recombinant human-derived Insulin-like 3/INSL3 protein, expressed by HEK293, with C-His labeled tag.
  • HY-P71805

    Ins1; Ins-1; insulin-1

    Mouse P. pastoris
    Insulin-1 is an important regulator of glucose and can effectively lower blood sugar by increasing cellular permeability to simple sugars, amino acids, and fatty acids.Its effects include accelerating glycolysis, promoting pentose phosphate cycle, and promoting hepatic glycogen synthesis.Insulin-1/Ins1 Protein, Mouse (P.pastoris, Myc, His) is the recombinant mouse-derived Insulin-1/Ins1 protein, expressed by P.pastoris , with C-Myc, N-6*His labeled tag.
  • HY-P70833

    Early Placenta insulin-Like Peptide; EPIL; insulin-Like Peptide 4; Placentin; INSL4

    Human HEK293
    The INSL4 protein plays a potentially critical role in the regulation of trophoblast development and bone formation. The specific mechanism of trophoblast development deserves further study. INSL4 Protein, Human (HEK293, His) is the recombinant human-derived INSL4 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P70291

    rHuinsulin-degrading enzyme/IDE, His ; insulin-Degrading Enzyme; Abeta-Degrading Protease; insulin Protease; insulinase; Insulysin; IDE

    Human HEK293
    Insulin/IDE protein is the key to the decomposition of cellular peptides. It participates in the degradation of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kinins and other peptides, and affects intercellular peptide signaling. Substrate binding induces conformational changes that promote degradation of larger substrates such as insulin. Insulysin/IDE Protein, Human (HEK293, His) is the recombinant human-derived Insulysin/IDE protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P76455

    insulin-like peptide INSL6; Relaxin/insulin-like factor 1; INSL6; RIF1

    Human HEK293
    The INSL6 protein plays a crucial role in sperm development and fertilization, highlighting its importance in male reproductive biology. Its potential function in promoting sperm development and successful fertilization emphasizes its importance in reproductive physiology. INSL6 Protein, Human (HEK293, His) is the recombinant human-derived INSL6 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P701241

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Others E. coli
    IGF-I protein is similar to insulin and exerts effective growth-promoting activity as a ligand of IGF1R. Binding to the α subunit of IGF1R activates intrinsic tyrosine kinase, triggering autophosphorylation of the β subunit. IGF-I Protein, Salmon is the recombinant IGF-I protein, expressed by E. coli , with tag free.
  • HY-P70698
    IGF-I/IGF-1 Protein, Mouse (His)
    4 Publications Verification

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Mouse E. coli
    IGF-I/IGF-1 Protein, Mouse (His) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF1 also mediates neuroprotective mechanism.
  • HY-P70698A

    IGF1; IGF-1; insulin-like growth factor 1; insulin-like growth factor I; Somatomedin C; somatomedin-C

    Mouse E. coli
    The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. IGF-I/IGF-1 Protein, Mouse (N-His) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P702944

    insulin receptor substrate 1; IRS-1

    Human E. coli
    IRS1 Protein, Human (GST) is the recombinant human-derived IRS1, expressed by E. coli , with GST labeled tag. ,
  • HY-P73906

    insulin-like growth factor II; IGF-II; Preptin; IGF2; PP1446

    Human P. pastoris
    The IGF2 protein is an important member of the insulin-like growth factor family and plays an important role in mammalian growth, fetoplacental development, and adult glucose metabolism. Regulated by placental prolactin, affecting tissue differentiation. IGF2 Protein, Human (P.pastoris) is the recombinant human-derived IGF2 protein, expressed by P. pastoris , with tag free.
  • HY-P76410

    insulin-like growth factor-binding protein 5; IGFBP5

    Canine HEK293
    IGFBP-5 is only one of a family of six IGFBPs. IGFBP-5 is a 29 kDa phosphorylated and glycosylated protein, which is secreted by a wide variety of cell types during different growth conditions. IGFBP-5, the most conserved IGFBP, is the major protein secreted by skeletal muscles. IGFBP-5 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IGFBP-5 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P77395

    insulin growth factor-like family member 2; IGFL2

    Human HEK293
    The IGFL2 protein emerged as a potential ligand for the IGFLR1 cell membrane receptor, suggesting a role in mediating cell signaling events. As a putative ligand, IGFL2 is primed to interact with the IGFLR1 receptor, suggesting involvement in cellular responses and signaling cascades. IGFL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFL2 protein, expressed by HEK293 , with N-hFc labeled tag.
  • HY-P72256

    CD221; CD221 antigen ; IGF 1 receptor; IGF 1R; IGF I receptor; IGF-I receptor; Igf1r; IGF1R_HUMAN; IGFIR; IGFIRC; IGFR; insulin like growth factor 1 receptor; insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor beta chain; insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; Soluble IGF1R variant 1; Soluble IGF1R variant 2

    Human E. coli
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P74848

    insulin-like growth factor-binding protein 1; IGFBP1

    Rhesus Macaque HEK293
    IGFBP-1 Protein, a member of the insulin-like growth factor-binding protein (IGFBP) family, extends IGFs' half-life and modulates their growth-promoting effects on cell culture, inhibiting or stimulating these responses. Crucially, it alters the interaction between IGFs and their cell surface receptors and promotes cell migration. Notably versatile, IGFBP-1 shows equal binding affinity for both IGF1 and IGF2, underscoring its diverse role in modulating the biological activities of insulin-like growth factors. IGFBP-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P77395A

    insulin growth factor-like family member 2; IGFL2

    Human HEK293
    The IGFL2 protein emerged as a potential ligand for the IGFLR1 cell membrane receptor, suggesting a role in mediating cell signaling events. As a putative ligand, IGFL2 is primed to interact with the IGFLR1 receptor, suggesting involvement in cellular responses and signaling cascades. IGFL2 Protein, Human (HEK293, N-hFc) is the recombinant human-derived IGFL2, expressed by HEK293, with N-hFc labeled tag. The total length of IGFL2 Protein, Human (HEK293, N-hFc) is 94 a.a..
  • HY-P700241AF

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Pig E. coli
    The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
  • HY-P706010

    Igf1; Igf-1insulin-like growth factor I; IGF-I; Somatomedin

    Rat E. coli
  • HY-P74849

    insulin-like growth factor-binding protein 1; PP12; IBP-1;

    Canine HEK293
    IGFBP-1 Protein is a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth factor (IGFs) I and II to extend the half-life of IGFs. IGFBP-1 inhibits proliferation, invasion, migration and apoptosis of HTR-8/SVneo cells by inducing MMP-26 expression. IGFBP1 may be a new prognostic factor and a target of molecular targeted therapy for gastric cancer. IGFBP-1 Protein, Canine (HEK293, His) is the recombinant canine-derived IGFBP-1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74843

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Mouse P. pastoris
    IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with tag free.
  • HY-P703573

    insulin receptor substrate 1; IRS1; Homo sapiens; Human; IRS-1; Transducer

    Human E. coli
    IRS1 Protein, Human (His, Strep) is the recombinant human-derived IRS1, expressed by E. coli , with Strep, His labeled tag. ,
  • HY-P73136

    insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Human HEK293
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag.
  • HY-P73140

    insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5

    Human Sf9 insect cells
    The IGFBP-5 protein regulates insulin-like growth factor (IGF) and extends its lifespan. It can inhibit or stimulate the growth-promoting effect of IGF, showing its dual regulatory function. IGFBP-5 Protein, Human (sf9, His) is the recombinant human-derived IGFBP-5 protein, expressed by Sf9 insect cells , with C-His labeled tag.
  • HY-P73141

    insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6

    Human HEK293
    IGFBP-6 protein is an important IGFBP member that regulates insulin-like growth factor (IGF) by changing its interaction with cell surface receptors, thereby affecting IGF-induced growth responses. In addition to regulating IGF signaling, IGFBP-6 also activates the MAPK pathway and induces cell migration. IGFBP-6 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P73142

    insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF

    Human HEK293
    IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P73905

    insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IBP6

    Rat HEK293
    IGFBP-6 protein modulates IGFs' activity, extending their half-life and exhibiting dual regulatory capacity.It activates the MAPK pathway, induces cell migration, and interacts with PHB2.These diverse functions emphasize IGFBP-6's multifaceted role in cellular responses related to growth regulation, signaling, and migration.IGFBP-6 Protein, Rat (HEK293, His) is the recombinant rat-derived IGFBP-6 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P77394

    insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5

    Cynomolgus HEK293
    IGFBP-5 protein modulates IGFs, extending their life span and regulating their growth effects. It inhibits or stimulates IGFs, showing its dual function. By altering IGFs' interaction with cell receptors, IGFBP-5 fine-tunes growth-associated signaling pathways, governing cellular responses. This interplay reveals IGFBP-5's multifaceted role in cellular growth and proliferation. IGFBP-5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-5 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P705603

    INSRR; IRR; IR-related receptor; insulin receptor-related protein; EC:2.7.10.1

    Human Sf9 insect cells
  • HY-P73138

    insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3

    Human HEK293
    IGFBP-3 protein is a part of IGFBP that significantly prolongs IGF half-life and modulates growth effects in cell culture. It inhibits or stimulates IGF-induced cellular responses by changing the kinetics of interaction with cell surface receptors. IGFBP-3 Protein, Human (HEK293, His) is the recombinant human-derived IGFBP-3 protein, expressed by HEK293 , with N-His labeled tag.
  • HY-P74844

    IBP-7; IGFBP7; IGFBP-7v; insulin-like growth factor binding protein 7

    Mouse HEK293
    IGFBP-7 Protein is a member of the insulin-like growth factor binding protein (IGFBP) Family. The major function of IGFBP-7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 exhibits a relatively low affinity for binding to both IGF-I and IGF-II. Furthermore, it has the capacity to stimulate the production of prostacyclin (PGI2) and enhance cell adhesion. IGFBP-7 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-7 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P74845

    BP-4; HT29-IGFBP; IBP4; insulin-like growth factor-binding protein 4

    Mouse HEK293
    IGFBP-4 protein modulates IGFs' activity and can either inhibit or stimulate their growth-promoting effects. It alters the interaction between IGFs and their receptors, with a preference for binding to IGF2. This highlights the nuanced role of IGFBP-4 in fine-tuning IGF-mediated cellular responses. IGFBP-4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-4 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74846

    IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53

    Mouse HEK293
    IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74847

    IBP-2; insulin-like growth factor binding protein 2; IGFBP2; IGF-BP53

    Mouse HEK293
    IGFBP-2 protein, a member of the IGF-binding protein family, inhibits IGF-mediated growth and developmental rates. It can extend the half-life of IGF and exhibit dual functions by inhibiting or stimulating the growth-promoting effect of IGF in cell culture. IGFBP-2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IGFBP-2 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P700185AF

    insulin-like growth factor 2; Multiplication-stimulating polypeptide; IGF-II; Igf-2; Igf2

    Mouse E. coli
    The IGF-II protein plays a crucial role in glucose-mediated insulin secretion, acting together with insulin as a physiological amplifier. Furthermore, it exhibits osteogenic properties by enhancing osteoblast mitotic activity through phosphorylation of MAPK1 and MAPK3. Animal-Free IGF-II Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-II protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.
  • HY-P703840

    insulin-like growth factor-binding protein 3; IGF-BP3; IBP-3; IGFBP-3

    Cynomolgus HEK293
    IGFBP-3 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-3 protein, expressed by HEK293, with N-His tag.
  • HY-P72606

    insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221

    Human HEK293
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P703906

    insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF

    Human HEK293
    IGFBP-7 Protein, with relatively low IGF-I and IGF-II affinity, stimulates prostacyclin (PGI2) production and enhances cell adhesion. The significance of its interaction with VPS24/CHMP3 remains uncertain and warrants further investigation. IGFBP-7 Protein, Human (Biotinylated, HEK293, hFc, Avi) is the recombinant human-derived IGFBP-7 protein, expressed by HEK293, with Avi and C-hFc labeled tag.
  • HY-P704676

    insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221

    Human HEK293
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, Fc) is the recombinant human-derived IGF-I R protein, expressed by HEK293, with C-hFc labeled tag.
  • HY-P705032

    insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF

    Human HEK293
  • HY-P70357

    rMuinsulin-like growth factor-binding protein 6/IGFBP-6, His; insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6; Igfbp6; IBP6; IGF binding protein 6; insulin-like growth factor-binding protein 6

    Mouse HEK293
    IGFBP-6 protein can extend the half-life of IGF and regulate its effects. It can inhibit or stimulate the growth-promoting effects of IGF. IGFBP-6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-6 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P74442

    insulin-like growth factor 1 receptor; IGF-I receptor; CD221; IGF1R

    Human HEK293
    IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag.

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