IDE-IN-2
Based on 1 publication(s) in Google Scholar
IDE-IN-2 (Compound 4) is an inhibitor for insulin-degrading enzyme. IDE-IN-2 is predicted to have CYP3A4, CYP2C19, hERG, NADP+, HIF1α and histidine kinase inhibitory activities, and has potential biological activity in anti-diabetic, anti-tumor, anti-bacterial aspects, according to the in silico prediction.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 49619-58-1
- Formula: C13H12O3
- Molecular Weight:216.23
-
Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) IDE-IN-2
More
Biological Activity
Chemical Information
-
CAS No. 49619-58-1
-
Appearance Solid
-
Molecular Weight 216.23
-
Formula C13H12O3
-
Color Light yellow to yellow
-
SMILES
CC(C)C1=CC2=C(C=C1)OC=C(C=O)C2=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Mol Biomed
ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity. [Abstract]2025 Nov 13;6(1):108. PMID: 41231359
Solvent & Solubility
DMSO : 100 mg/mL (462.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6247 mL | 23.1235 mL | 46.2471 mL | 115.6176 mL |
| 5 mM | 0.9249 mL | 4.6247 mL | 9.2494 mL | 23.1235 mL | |
| 10 mM | 0.4625 mL | 2.3124 mL | 4.6247 mL | 11.5618 mL | |
| 15 mM | 0.3083 mL | 1.5416 mL | 3.0831 mL | 7.7078 mL | |
| 20 mM | 0.2312 mL | 1.1562 mL | 2.3124 mL | 5.7809 mL | |
| 25 mM | 0.1850 mL | 0.9249 mL | 1.8499 mL | 4.6247 mL | |
| 30 mM | 0.1542 mL | 0.7708 mL | 1.5416 mL | 3.8539 mL | |
| 40 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8904 mL | |
| 50 mM | 0.0925 mL | 0.4625 mL | 0.9249 mL | 2.3124 mL | |
| 60 mM | 0.0771 mL | 0.3854 mL | 0.7708 mL | 1.9270 mL | |
| 80 mM | 0.0578 mL | 0.2890 mL | 0.5781 mL | 1.4452 mL | |
| 100 mM | 0.0462 mL | 0.2312 mL | 0.4625 mL | 1.1562 mL |
Powered by Bioz