1. Metabolic Enzyme/Protease
  2. Glucokinase
  3. MK-0941

MK-0941 

Cat. No.: HY-19843
Handling Instructions

MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes.

For research use only. We do not sell to patients.

MK-0941 Chemical Structure

MK-0941 Chemical Structure

CAS No. : 1137916-97-2

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Description

MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes[1].

IC50 & Target

EC50: 240 nM (Recombinant human glucokinase, 2.5 mM glucose), 65 nM (Recombinant human glucokinase, 10 mM glucose)[1]

Molecular Weight

556.61

Formula

C₂₂H₂₈N₄O₉S₂

CAS No.

1137916-97-2

SMILES

CS(=O)(O)=O.O=C(NC1=NN(C)C=C1)C2=CC(O[[email protected]@H](C)CO)=CC(OC3=CC=C(S(=O)(CC)=O)N=C3)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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MK-0941
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HY-19843
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