6-(Dimethylamino)purine (Standard)
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis).
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 938-55-6
- Formula: C7H9N5
- Molecular Weight:163.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 938-55-6
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Molecular Weight 163.18
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Formula C7H9N5
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SMILES
CN(C)C1=C2NC=NC2=NC=N1
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Synonyms
6-Dimethylaminopurine (Standard); 6-DMAP (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Szöllösi MS, et al. Inhibition of protein kinases by 6-dimethylaminopurine accelerates the transition to interphase in activated mouse oocytes. J Cell Sci. 1993 Mar;104 ( Pt 3):861-72. [Content Brief]
[2]. Ledda S, et al. The effect of 6-dimethylaminopurine (6-DMAP) on DNA synthesis in activated mammalian oocytes. Zygote. 1996 Feb;4(1):7-9. [Content Brief]
[3]. Bayat-Sarmadi M, et al. 6-Dimethyl amino purine and 2-amino purine inhibit the induction of expression of milk protein genes by prolactin. Biosci Rep. 1992 Jun;12(3):189-97. [Content Brief]
[4]. Ogneva IV. Mouse and Fly Sperm Motility Changes Differently under Modelling Microgravity. Curr Issues Mol Biol. 2021 Jul 5;43(2):590-604. [Content Brief]
[5]. Nakashima M, et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells. Anticancer Res. 2008 Mar-Apr;28(2A):609-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-(Dimethylamino)purine (Standard) Related Classifications
HY-W010128R Related Classifications
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