C25 Ceramide (d18:1/25:0) 

C25 Ceramide (d18:1/25:0) is an endogenous ultra-long-chain ceramide that antagonizes the detrimental effects of long-chain ceramides on insulin sensitivity. C25 Ceramide (d18:1/25:0) is specifically enriched in oxidative skeletal muscle fibers, where it serves dual roles in providing structural support to cell membranes and regulating cellular signaling. By participating in the regulation of lipid homeostasis within muscle fibers, C25 Ceramide (d18:1/25:0) helps maintain normal insulin signaling. C25 Ceramide (d18:1/25:0) is primarily utilized in research concerning metabolic diseases—particularly in mechanistic studies investigating the muscle fiber type-specific aspects of insulin resistance^[1].

The levels of C25 Ceramide (d18:1/25:0) are positively correlated with good insulin sensitivity in the body^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

664.14

C₄₃H₈₅NO₃

67492-18-6

CCCCCCCCCCCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Eurén T, et al. Ceramide Metabolism in Oxidative and Glycolytic Muscle: Significance for Lipid-Induced Insulin Resistance[J]. Available at SSRN 5803142.