Glycybenzofuran
Glycybenzofuran is a flavonoid. Glycybenzofuran can be isolated from G. uralensis. Glycybenzofuran is a potent, competitive, selective PTP1B inhibitor. Glycybenzofuran shows excellent inhibitory selectivity against PTP1B. Glycybenzofuran increases insulin-stimulated pAkt levels. Glycylbenzofuran can be used in the research of hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 1253641-15-4
- Formula: C21H22O5
- Molecular Weight:354.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1253641-15-4
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Molecular Weight 354.40
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Formula C21H22O5
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SMILES
OC1=CC(OC(C2=C(C=C(C(C/C=C(C)\C)=C2OC)O)O)=C3C)=C3C=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hosseinzadeh H, et al. Pharmacological Effects of Glycyrrhiza spp. and Its Bioactive Constituents: Update and Review. Phytother Res. 2015 Dec;29(12):1868-86. [Content Brief]
[2]. Li W, et al. Evaluation of licorice flavonoids as protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5836-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)