2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. 3-Hydroxyproline

3-Hydroxyproline is a non-glycosyl microbial α-glucosidase inhibitor. 3-Hydroxyproline is used in the research of diabetes (type 2 diabetes/non-insulin-dependent diabetes mellitus).

For research use only. We do not sell to patients.

3-Hydroxyproline

3-Hydroxyproline Chemical Structure

CAS No. : 567-36-2

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3-Hydroxyproline Related Antibodies

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Description

3-Hydroxyproline is a non-glycosyl microbial α-glucosidase inhibitor. 3-Hydroxyproline is used in the research of diabetes (type 2 diabetes/non-insulin-dependent diabetes mellitus)[1].

In Vitro

3-Hydroxyproline (Compound 2) (1.5 mg/mL; 20 min pre-incubation, 40 min reaction incubation) potently inhibits Saccharomyces cerevisiae α-glucosidase (IC50 = 5.3 μg/mL), effectively inhibits rat intestinal α-glucosidase (IC50 = 100 μg/mL) and Bacillus stearothermophilus α-glucosidase (IC50 = 142 μg/mL), and shows no activity against rice α-glucosidase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Hydroxyproline Related Antibodies
Molecular Weight

131.13

Formula

C5H9NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1NCCC1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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3-Hydroxyproline Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Hydroxyproline567-36-2GlycosidaseSaccharomyces cerevisiaenon-insulin dependent diabetes mellitusα-glucosidasediabetes mellitusrice α-glucosidasetype 2 diabetesrat intestinal α-glucosidaseBacillus stearothermophilusInhibitorinhibitorinhibit

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