1. GPCR/G Protein
  2. Cannabinoid Receptor

CB1-IN-1 

Cat. No.: HY-12790 Purity: >98.0%
Data Sheet SDS Handling Instructions

CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively.

For research use only. We do not sell to patients.
CB1-IN-1 Chemical Structure

CB1-IN-1 Chemical Structure

CAS No. : 1429239-98-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 496 In-stock
5 mg USD 420 In-stock
10 mg USD 600 In-stock
50 mg USD 1800 In-stock
100 mg USD 2520 Get quote
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0.3 nM (Ki, CB1R) 21 nM (Ki, CB2R) Target: CB1R in vivo: CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.3304 mL 6.6519 mL 13.3037 mL
5 mM 0.2661 mL 1.3304 mL 2.6607 mL
10 mM 0.1330 mL 0.6652 mL 1.3304 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

751.67

Formula

C₃₃H₃₁Cl₂F₃N₆O₃S₂

CAS No.

1429239-98-4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
CB1-IN-1
Cat. No.:
HY-12790
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