LMPTP IN-2
LMPTP IN-2 is a selective protein tyrosine phosphatase (LMPTP) inhibitor with an IC50 of 0.020 μM. LMPTP IN-2 exerts inhibitory effects through a non-competitive mechanism. LMPTP IN-2 can be used for research on obesity-related insulin resistance and type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 2361515-53-7
- Formula: C19H15Cl2N5
- Molecular Weight:384.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
LMPTP IN-2 (compound 5d) binds to the entrance of the catalytic pocket of recombinant human LMPTP, forming key hydrophobic interactions, π-π stacking interactions, and hydrogen bond interactions, thereby blocking the accessibility of the active site and providing support for its non-competitive inhibition mechanism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2361515-53-7
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Molecular Weight 384.26
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Formula C19H15Cl2N5
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SMILES
ClC1=CC=CC(Cl)=C1CN2C=NC(N)=C3N=C(C4=CC=CC=C4C)N=C32
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)