1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Trehalulose

Trehalulose is a microbial metabolite and a beneficial structural isomer of Sucrose (HY-B1779). Trehalulose attenuates blood glucose and insulin response. Trehalulose exhibits antioxidant activity to support oxidative stability. Trehalulose can be used for food and beverage applications, and can be used for the research of dental caries, diabetes, obesity.

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Trehalulose

Trehalulose Chemical Structure

CAS No. : 51411-23-5

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Description

Trehalulose is a microbial metabolite and a beneficial structural isomer of Sucrose (HY-B1779). Trehalulose attenuates blood glucose and insulin response. Trehalulose exhibits antioxidant activity to support oxidative stability. Trehalulose can be used for food and beverage applications, and can be used for the research of dental caries, diabetes, obesity[1][2].

IC50 & Target[1]

Microbial Metabolite

 

In Vitro

Trehalulose (1.25-5 %) activates human epidermal fibroblast cells and reduces UV-induced oxidative stress[1].
Trehalulose (1%) minimally inhibits the activity of α-glucosyltransferase from Pseudomonas mesoacidophila MX-45, reducing relative activity to 98% of the control[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Trehalulose (1.47 g/kg bw; p.o.; daily; 26 weeks) is efficiently digested in rat intestinal systems via hydrolysis by the sucrase-isomaltase complex, with no significant adverse effects observed[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats[1]
Dosage: 1.47 g/kg bw
Administration: p.o.; daily; 26 weeks
Result: Was hydrolyzed into glucose and fructose by the sucrase-isomaltase complex in the rat intestinal system.
Showed efficient digestibility.
Caused no significant side effects such as diarrhea even after prolonged intake for 26 weeks.
Molecular Weight

342.30

Formula

C12H22O11

CAS No.
SMILES

O(CC([C@H]([C@@H]([C@@H](CO)O)O)O)=O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Structure Classification
Initial Source

Pseudomonas mesoacidophila MX-45

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Trehalulose
Cat. No.:
HY-133202
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