2. Apoptosis
  3. Necroptosis Apoptosis
  4. Cyclamic acid calcium

Cyclamic acid calcium  (Synonyms: Cyclohexylsulfamic acid calcium; Cyclamate calcium)

Cat. No.: HY-W719824
Handling Instructions Technical Support

Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine.

For research use only. We do not sell to patients.

Cyclamic acid calcium

Cyclamic acid calcium Chemical Structure

CAS No. : 139-06-0

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Other Forms of Cyclamic acid calcium:

Cyclamic acid calcium Related Antibodies

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Description

Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine[1][2][3][4][5].

In Vitro

Cyclamic acid (0-0.1 μM, 24-72 h) calcium causes the apoptosis of osteoblast cells and shows significant inhibition of osteoblasts[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cyclamic acid calcium Related Antibodies
In Vivo

Cyclamic acid (2-4 g/kg, p.o., daily for 2 weeks) calcium occurs diarrhea in dogs[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

219.02

Formula

C6H13NO3S·1/2Ca
CAS No.
SMILES

O=S(NC1CCCCC1)([O-])=O.[Ca+2].[1/2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cyclamic acid calcium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclamic acid139-06-0Cyclohexylsulfamic acidCyclamateNecroptosisApoptosisInhibitorinhibitorinhibit

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