139-06-0
Chemical Structure
Cyclamic acid calcium
Synonym(s): Cyclohexylsulfamic acid calcium; Cyclamate calcium
- CAS No.: 139-06-0
- Formula:C6H13NO3S·1/2Ca
- Molecular Weight:219.02
SMILES: O=S(NC1CCCCC1)([O-])=O.[Ca+2].[1/2]
Biological Activity: Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine[1][2][3][4][5].
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Cyclamic acid calcium | Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine. | |||||||||||||||||||||
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Keywords
