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Cat. No.: HY-P87558

Insulin Receptor R Antibody (YA7242)

Insulin Receptor R Antibody (YA7242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Insulin Receptor R.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue
Dilution Ratio	1:1000-2000	1:100-200	1:100-200	1:100-200

Description

Insulin Receptor R Antibody (YA7242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Insulin Receptor R.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human Predicted Reactivity: Mouse,Rat

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
Observed Molecular Weight

Observed band size: 80 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 144 kDa

Immunogen

A synthesized peptide derived from human Insulin receptor related protein

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Insulin Receptor R receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB
Subcellular Localization

Membrane
Isoforms & Post-Translational Modification

P14616: 1297 amino acids, molecular weight 143720 Da.
Subunit

Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds
SwissProt ID

P14616