3-Aminoisobutyric acid sodium salt
Based on 1 Customer Validation
3-Aminoisobutyric acid (β-Aminoisobutyric acid) sodium salt has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid sodium salt increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid sodium salt attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid sodium salt is a catabolic metabolite of thymine and valine in skeletal muscle.
For research use only. We do not sell to patients.
- Purity : 99.59%
- CAS No.: 84796-61-2
- Formula: C4H8NNaO2
- Molecular Weight:125.10
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 84796-61-2
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Appearance Solid
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Molecular Weight 125.10
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Formula C4H8NNaO2
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Color White to off-white
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SMILES
NCC(C(O[Na])=O)C
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Synonyms
β-Aminoisobutyric acid sodium salt; BAIBA sodium salt
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 70 mg/mL (559.55 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Roberts LD, et al. β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 7;19(1):96-108. [Content Brief]
[2]. Jung TW, et al. BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice. Diabetologia. 2015 Sep;58(9):2096-105. [Content Brief]
[3]. Audzeyenka I, et al. β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes. Sci Rep. 2023 Jan 14;13(1):766. [Content Brief]
[4]. Yi X, et al. Signaling metabolite β-aminoisobutyric acid as a metabolic regulator, biomarker, and potential exercise pill. Front Endocrinol (Lausanne). 2023 May 29;14:1192458. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.9936 mL | 39.9680 mL | 79.9361 mL | 199.8401 mL |
| 5 mM | 1.5987 mL | 7.9936 mL | 15.9872 mL | 39.9680 mL | |
| 10 mM | 0.7994 mL | 3.9968 mL | 7.9936 mL | 19.9840 mL | |
| 15 mM | 0.5329 mL | 2.6645 mL | 5.3291 mL | 13.3227 mL | |
| 20 mM | 0.3997 mL | 1.9984 mL | 3.9968 mL | 9.9920 mL | |
| 25 mM | 0.3197 mL | 1.5987 mL | 3.1974 mL | 7.9936 mL | |
| 30 mM | 0.2665 mL | 1.3323 mL | 2.6645 mL | 6.6613 mL | |
| 40 mM | 0.1998 mL | 0.9992 mL | 1.9984 mL | 4.9960 mL | |
| 50 mM | 0.1599 mL | 0.7994 mL | 1.5987 mL | 3.9968 mL | |
| 60 mM | 0.1332 mL | 0.6661 mL | 1.3323 mL | 3.3307 mL | |
| 80 mM | 0.0999 mL | 0.4996 mL | 0.9992 mL | 2.4980 mL | |
| 100 mM | 0.0799 mL | 0.3997 mL | 0.7994 mL | 1.9984 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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