3-Aminoisobutyric acid sodium salt (Synonyms: β-Aminoisobutyric acid sodium salt; BAIBA sodium salt)

Cat. No.: HY-165098 Purity: 99.59%: Data Sheet
COA

SDS
Handling Instructions
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3-Aminoisobutyric acid (β-Aminoisobutyric acid) sodium salt has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid sodium salt increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid sodium salt attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid sodium salt is a catabolic metabolite of thymine and valine in skeletal muscle.

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3-Aminoisobutyric acid sodium salt Chemical Structure

CAS No. : 84796-61-2

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Other Forms of 3-Aminoisobutyric acid sodium salt:

3-Aminoisobutyric acid In-stock

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Purity & Documentation
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Description

Molecular Weight

125.10

Formula

C₄H₈NNaO₂

CAS No.

84796-61-2

Appearance

Solid

Color

White to off-white

SMILES

NCC(C(O[Na])=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 70 mg/mL (559.55 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.9936 mL	39.9680 mL	79.9361 mL
5 mM	1.5987 mL	7.9936 mL	15.9872 mL
10 mM	0.7994 mL	3.9968 mL	7.9936 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.59%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (243 KB) HNMR (230 KB) LCMS (89 KB)

Handling Instructions (2659 KB)

References

[1]. Roberts LD, et al. β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014 Jan 7;19(1):96-108. [Content Brief]

[2]. Jung TW, et al. BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice. Diabetologia. 2015 Sep;58(9):2096-105. [Content Brief]

[3]. Audzeyenka I, et al. β-Aminoisobutyric acid (L-BAIBA) is a novel regulator of mitochondrial biogenesis and respiratory function in human podocytes. Sci Rep. 2023 Jan 14;13(1):766. [Content Brief]

[4]. Yi X, et al. Signaling metabolite β-aminoisobutyric acid as a metabolic regulator, biomarker, and potential exercise pill. Front Endocrinol (Lausanne). 2023 May 29;14:1192458. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	7.9936 mL	39.9680 mL	79.9361 mL	199.8401 mL
	5 mM	1.5987 mL	7.9936 mL	15.9872 mL	39.9680 mL
	10 mM	0.7994 mL	3.9968 mL	7.9936 mL	19.9840 mL
	15 mM	0.5329 mL	2.6645 mL	5.3291 mL	13.3227 mL
	20 mM	0.3997 mL	1.9984 mL	3.9968 mL	9.9920 mL
	25 mM	0.3197 mL	1.5987 mL	3.1974 mL	7.9936 mL
	30 mM	0.2665 mL	1.3323 mL	2.6645 mL	6.6613 mL
	40 mM	0.1998 mL	0.9992 mL	1.9984 mL	4.9960 mL
	50 mM	0.1599 mL	0.7994 mL	1.5987 mL	3.9968 mL
	60 mM	0.1332 mL	0.6661 mL	1.3323 mL	3.3307 mL
	80 mM	0.0999 mL	0.4996 mL	0.9992 mL	2.4980 mL
	100 mM	0.0799 mL	0.3997 mL	0.7994 mL	1.9984 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

3-Aminoisobutyric acid sodium salt Related Classifications

Metabolic Disease Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Aminoisobutyric acid84796-61-2β-Aminoisobutyric acidBAIBAEndogenous MetaboliteInhibitorinhibitorinhibit

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