cis-NVP-ADW742
cis-NVP-ADW742 (cis-ADW742) is a cis isomer of NVP-ADW742 (HY-10252). NVP-ADW742 is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.
For research use only. We do not sell to patients.
- CAS No.: 475489-15-7
- Formula: C28H31N5O
- Molecular Weight:453.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 475489-15-7
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Molecular Weight 453.58
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Formula C28H31N5O
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SMILES
NC1=C2C(N([C@H]3C[C@@H](CN4CCCC4)C3)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1
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Synonyms
cis-ADW742; cis-GSK 552602A; cis-ADW
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
cis-NVP-ADW742 Related Classifications
HY-10252A Related Classifications
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