EGFR-IN-146
EGFR-IN-146 is an EGFR inhibitor that can inhibit the EGFR signaling pathway and improve insulin sensitivity by activating the AMPK pathway, which can effectively reduce blood sugar levels and body weight. EGFR-IN-146 has great potential in the study of diabetes and obesity.
For research use only. We do not sell to patients.
- CAS No.: 166039-38-9
- Formula: C20H16N4
- Molecular Weight:312.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EGFR-IN-146 (Compound 53) (10 μM) effectively promotes glucose absorption and plays a role in lowering blood sugar in the C2C12 cell model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 166039-38-9
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Molecular Weight 312.37
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Formula C20H16N4
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SMILES
C1(CNC2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)=CC=CN=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)