K-111
K-111 (BM-170744) is an oral active PPAR alpha agonist. K-111 show efficacy in improving insulin resistance, reducing body weight, and ameliorating atherogenic dyslipidemia. K-111 can be used for study of type 2 diabetes, dyslipidaemia, obesity and the metabolic syndrome.
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- No. CAS: 221564-97-2
- Fòrmula: C18H25Cl3O2
- Peso molecular:379.75
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 221564-97-2
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Peso molecular 379.75
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Fòrmula C18H25Cl3O2
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SMILES
O=C(C(Cl)(CCCCCCCCCCC1=CC=C(C=C1)Cl)Cl)O
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Synonyms
BM 17.0744
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Schäfer SA, et al. Biochemical and morphological effects of K-111, a peroxisome proliferator-activated receptor (PPAR)alpha activator, in non-human primates. Biochem Pharmacol. 2004;68(2):239-251. [Content Brief]
[2]. Ortmeyer HK, et al. Skeletal muscle glycogen synthase subcellular localization: effects of insulin and PPAR-alpha agonist (K-111) administration in rhesus monkeys. Am J Physiol Regul Integr Comp Physiol. 2005;288(6):R1509-R1517. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
K-111 Related Classifications
HY-120943 Related Classifications
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Keywords
- K-111
- 221564-97-2
- BM 17.0744
- K111
- K 111
- PPAR
- K-111 (BM-170744) is an oral active PPAR alpha agonist. K-111 show efficacy in improving insulin resistance
- reducing body weight
- and ameliorating atherogenic dyslipidemia. K-111 can be used for study of type 2 diabetes
- dyslipidaemia
- obesity and the metabolic syndrome[1][2].
- Inhibitor
- inhibitor
- inhibit