Cevoglitazar
Based on 1 Customer Validation
Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 97.00%
- CAS No.: 839673-52-8
- 화학식: C27H21F3N2O6S
- 분자량:558.53
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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PPARα |
PPARγ |
Chemical Information
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CAS No. 839673-52-8
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Appearance Solid
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분자량 558.53
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화학식 C27H21F3N2O6S
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Color White to off-white
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SMILES
O=C([C@@H]1N(S(=O)(C2=CC=C(OCC3=C(C)OC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2)=O)C5=C(C=CC=C5)C1)O
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Synonyms
LBM-642
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (89.52 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7904 mL | 8.9521 mL | 17.9041 mL | 44.7604 mL |
| 5 mM | 0.3581 mL | 1.7904 mL | 3.5808 mL | 8.9521 mL | |
| 10 mM | 0.1790 mL | 0.8952 mL | 1.7904 mL | 4.4760 mL | |
| 15 mM | 0.1194 mL | 0.5968 mL | 1.1936 mL | 2.9840 mL | |
| 20 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2380 mL | |
| 25 mM | 0.0716 mL | 0.3581 mL | 0.7162 mL | 1.7904 mL | |
| 30 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4920 mL | |
| 40 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 50 mM | 0.0358 mL | 0.1790 mL | 0.3581 mL | 0.8952 mL | |
| 60 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7460 mL | |
| 80 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |