1. GPCR/G Protein
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  3. LSN3318839

LSN3318839 is an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R).

For research use only. We do not sell to patients.

LSN3318839 Chemical Structure

LSN3318839 Chemical Structure

CAS No. : 2764704-18-7

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1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 1040 In-stock
25 mg USD 2080 In-stock
50 mg USD 3300 In-stock
100 mg USD 5350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

LSN3318839 is an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R).

Molecular Weight

480.39

Formula

C26H23Cl2N3O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C[C@H](C1=CC=CC=C1C2=NC=C3N=CN(C3=C2)[C@@H](C4=C(C(C5CC5)=CC=C4Cl)Cl)C)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (20.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0816 mL 10.4082 mL 20.8164 mL
5 mM 0.4163 mL 2.0816 mL 4.1633 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0816 mL 10.4082 mL 20.8164 mL 52.0410 mL
5 mM 0.4163 mL 2.0816 mL 4.1633 mL 10.4082 mL
10 mM 0.2082 mL 1.0408 mL 2.0816 mL 5.2041 mL
15 mM 0.1388 mL 0.6939 mL 1.3878 mL 3.4694 mL
20 mM 0.1041 mL 0.5204 mL 1.0408 mL 2.6021 mL
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LSN3318839 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LSN3318839
Cat. No.:
HY-142162
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