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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1782 Results for "
TFA
" in MedChemExpress (MCE) Product Catalog:
Products (1782)
1782 Results for "TFA" in MCE Product Catalog:
248
248 Cited Publications
別名: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
126
126 Cited Publications
製品番号: HY-P1410A
Target:
98
98 Cited Publications
製品番号: HY-P1061A
CAS 番号: 2803948-60-7
研究分野:
74
45
45 Cited Publications
製品番号: HY-114118A
純度: 99.92%
42
42 Cited Publications
製品番号: HY-P0014B
Target:
研究分野:
34
研究分野:
Pyridostatin (RR82) TFA is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin TFA also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin TFA interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin TFA exhibits antiproliferative and antiviral activities. Pyridostatin TFA can be used in studies related to breast cancer, cervical cancer, and Zika virus infection .
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32
32 Cited Publications
製品番号: HY-P0023A
CAS 番号: 500577-51-5
27
Target:
研究分野:
26
26 Cited Publications
製品番号: HY-P0223A
Target:
研究分野:
26
Target:
ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 TFA blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 TFA is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 TFA reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1 .
24
24 Cited Publications
製品番号: HY-100574B
CAS 番号: 1043444-18-3
Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
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22 Cited Publications
製品番号: HY-16701A
BV6 TFA is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. BV6 TFA shows an IC50 of 7.2 μM in MTS assays in HCC193 cells. BV6 TFA can be used in the research of endometrial cancer and endometriosis .
22
Target:
22
22 Cited Publications
製品番号: HY-P1489A
CAS 番号: 1262751-08-5
Target:
研究分野:
19
19 Cited Publications
製品番号: HY-P1439A
Target:
研究分野:
18
AT7519 (AT7519M) TFA as a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
