AGA-(C8R) HNG17, humanin derivative TFA

Name: AGA-(C8R) HNG17, humanin derivative TFA
Brand: MedChemExpress
SKU: HY-P1851A
Rating: 4.5 (1 reviews)

Cat. No.: HY-P1851A Purity: 98.34%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

AGA-(C8R) HNG17, humanin derivative TFA Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of AGA-(C8R) HNG17, humanin derivative TFA:

AGA-(C8R) HNG17, humanin derivative Get quote

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Biological Activity
Purity & Documentation
References
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Description

AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults^[1].

Molecular Weight

1850.04

Formula

C₈₀H₁₃₅F₃N₂₀O₂₆

Appearance

Solid

Color

White to off-white

Sequence

Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro

Sequence Shortening

PAGASRLLLLTGEIDLP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (54.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 20 mg/mL (10.81 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5405 mL	2.7026 mL	5.4053 mL
5 mM	0.1081 mL	0.5405 mL	1.0811 mL
10 mM	0.0541 mL	0.2703 mL	0.5405 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.34%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (242 KB) RP-HPLC (227 KB) LCMS (127 KB) Elemental Analysis Report (101 KB)

Handling Instructions (2659 KB)

References

[1]. Chiba T, et al. Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo. J Neurosci. 2005 Nov 2;25(44):10252-61. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	0.5405 mL	2.7026 mL	5.4053 mL	13.5132 mL
	5 mM	0.1081 mL	0.5405 mL	1.0811 mL	2.7026 mL
	10 mM	0.0541 mL	0.2703 mL	0.5405 mL	1.3513 mL
DMSO	15 mM	0.0360 mL	0.1802 mL	0.3604 mL	0.9009 mL
	20 mM	0.0270 mL	0.1351 mL	0.2703 mL	0.6757 mL
	25 mM	0.0216 mL	0.1081 mL	0.2162 mL	0.5405 mL
	30 mM	0.0180 mL	0.0901 mL	0.1802 mL	0.4504 mL
	40 mM	0.0135 mL	0.0676 mL	0.1351 mL	0.3378 mL
	50 mM	0.0108 mL	0.0541 mL	0.1081 mL	0.2703 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AGA-(C8R) HNG17, humanin derivativeOthersInhibitorinhibitorinhibit

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AGA-(C8R) HNG17, humanin derivative TFA

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