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  2. Secretin (28-54), human TFA

Secretin (28-54), human TFA (Synonyms: Human secretin TFA)

Cat. No.: HY-P1465A Purity: 97.12%
Handling Instructions

Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Secretin (28-54), human TFA Chemical Structure

Secretin (28-54), human TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 120 In-stock
Estimated Time of Arrival: December 31
5 mg USD 360 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Secretin (28-54), human TFA:

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Description

Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors[1].

In Vitro

Secretin is a hormone produced and secreted from the endocrine S cells in response to the gastric acid and lipid components. Secretin potentiates enzyme secretion from the acinar cell. Secretin is also a putative mitogen to promote pancreatic growth. In the stomach and gall bladder, Secretin inhibits gastric emptying and acid release and stimulates biliary output of water and bicarbonate. Secretin elicits its biological effects by interacting with specific cell surface receptors[1].

Molecular Weight

3153.48

Formula

C₁₃₂H₂₂₁N₄₄F₃O₄₂

Sequence

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2

Sequence Shortening

HSDGTFTSELSRLREGARLQRLLQGLV-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Protect from light
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Secretin (28-54), humanHuman secretinOthersSecretinhumanreceptorsdigestivehormoneInhibitorinhibitorinhibit

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Secretin (28-54), human TFA
Cat. No.:
HY-P1465A
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