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Exendin-4

(Synonyms: Exenatide)
70 Cited Publications
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Based on 70 publication(s) in Google Scholar

Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.

For research use only. We do not sell to patients.

  • Purity: 99.89%
  • CAS No.: 141758-74-9
  • Formula: C184H282N50O60S
  • Molecular Weight:4186.57
  • Storage:

    Sealed storage, away from moisture and light, under nitrogen.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture and light, under nitrogen)

  • Exendin-4 Chemical Structure
    Exendin-4 Chemical Structure
  • Experimental Validation Results for Exendin-4
  • Experimental Validation Results for Exendin-4
  • Experimental Validation Results for Exendin-4
  • Experimental Validation Results for Exendin-4
  • Experimental Validation Results for Exendin-4
CAS No.: 141758-74-9
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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RT-PCRPK/PD AnalysisIn Vivo ImagingCell Proliferation/Viability Assay
  • PK/PD Analysis
  • In Vivo Imaging
  • RT-PCR
  • Cell Proliferation/Viability Assay
  • RT-PCR
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  • Exendin-4 Chemical Structure
    Exendin-4 Chemical Structure
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    Exendin-4 purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2025 Nov 25:57:646-659. [Abstract]

    Customer Validation
     Pharmacokinetics of Exendin-4 following oral versus subcutaneous administration in mice. (a) Experimental design: Fasted mice received either (i) oral PBS + exendin-4 capsule (1 mg/kg), (ii) oral nanofibrils (20 mg/mL, 200 µL) + exendin-4 capsule (1 mg/kg), or (iii) subcutaneous exendin-4 (0.1 mg/kg, pharmacological control). (b) Serum exendin-4 levels over 6 hours. (c) Corresponding AUC analysis (0-6 h).

  • 1/16

    Exendin-4 purchased from MedChemExpress. Usage Cited in: J Adv Res. 2025 Mar 10:S2090-1232(25)00174-2. [Abstract]

    Customer Validation
     Micro-CT images representing trabecular formation in control mice, mice with T2DM, mice with T2DM treated with Exendin-4 (20 mg/kg)/Metformin, and GLP-1R knockout mice with T2DM treated with Exendin-4 within a region of interest (ROI). n=6 mice per group. Con: control; T2DM: type 2 diabetes mellitus; Met: metformin; Ex-4: Exendin-4; Micro-CT: micro-computed tomography.

  • 1/16

    Exendin-4 purchased from MedChemExpress. Usage Cited in: Gut. 2023 Feb;72(2):314-324. [Abstract]

    Customer Validation
     Exendin-4 (2 nmol/kg/day) supplementation improves the metabolic defect of TGR5 KO fed western-style diet (WSD) enriched with oligofructose (OFS).

  • 1/16

    Exendin-4 purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2019 Oct 25;10:1230. [Abstract]

    Customer Validation
     Exendin-4 or FSK treatment reduces ER stress-induced β-cell viability. INS-1 cells are incubated with THAP (0.5 μM), with Eexendin-4.

  • 1/16

    Exendin-4 purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2019 Oct 25;10:1230. [Abstract]

    Customer Validation
     INS-1 cells are incubated with THAP (0.5 μM), H89, with Exendin-4 or FSK at indicated concentration for 24 h, then the IL-1β level is analyzed by qRT-PCR (n = 3).

  • Exendin-4