Human secretin
Based on 1 Customer Validation
Human secretin is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors.
For research use only. We do not sell to patients.
- Purity: 99.17%
- CAS No.: 108153-74-8
- Formula: C130H220N44O40
- Molecular Weight:3039.46
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human secretin receptor[1]
Secretin is a hormone produced and secreted from the endocrine S cells in response to the gastric acid and lipid components. Secretin potentiates enzyme secretion from the acinar cell. Secretin is also a putative mitogen to promote pancreatic growth. In the stomach and gall bladder, Secretin inhibits gastric emptying and acid release and stimulates biliary output of water and bicarbonate. Secretin elicits its biological effects by interacting with specific cell surface receptors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 108153-74-8
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Appearance Solid
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Molecular Weight 3039.46
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Formula C130H220N44O40
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Color White to off-white
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Synonyms
Secretin (28-54), (human)
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Sequence
His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2
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Sequence Shortening
HSDGTFTSELSRLREGARLQRLLQGLV-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (32.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.3290 mL | 1.6450 mL | 3.2901 mL | 8.2251 mL |
| 5 mM | 0.0658 mL | 0.3290 mL | 0.6580 mL | 1.6450 mL | |
| 10 mM | 0.0329 mL | 0.1645 mL | 0.3290 mL | 0.8225 mL | |
| 15 mM | 0.0219 mL | 0.1097 mL | 0.2193 mL | 0.5483 mL | |
| 20 mM | 0.0165 mL | 0.0823 mL | 0.1645 mL | 0.4113 mL | |
| 25 mM | 0.0132 mL | 0.0658 mL | 0.1316 mL | 0.3290 mL | |
| 30 mM | 0.0110 mL | 0.0548 mL | 0.1097 mL | 0.2742 mL |
Human secretin Related Classifications
HY-P1465 Related Classifications
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