2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. SMD-3040 TFA

SMD-3040 TFA is a selective degrader of SMARCA2. SMD-3040 TFA contains SMARCA2/4 ligands, linker and VHL ligands and can be used for PROTAC drug synthesis. SMD-3040 TFA exhibits strong tumor growth inhibition in tumor xenograft models.

For research use only. We do not sell to patients.

SMD-3040 TFA Chemical Structure

SMD-3040 TFA Chemical Structure

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1 mg USD 800 In-stock
5 mg USD 2000 In-stock
10 mg USD 3500 Get quote
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Based on 1 publication(s) in Google Scholar

Other Forms of SMD-3040 TFA:

SMD-3040 TFA Related Antibodies

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Description

SMD-3040 TFA is a selective degrader of SMARCA2. SMD-3040 TFA contains SMARCA2/4 ligands, linker and VHL ligands and can be used for PROTAC drug synthesis. SMD-3040 TFA exhibits strong tumor growth inhibition in tumor xenograft models[1].

Molecular Weight

1057.23

Formula

C54H67F3N10O7S
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N[C@H](C(N1[C@H](C(N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)C[C@@H](O)C1)=O)C(C)(C)C)[C@H]4CC[C@H](CN5CC6(CCC(N7N=CC(C8=C(N)N=NC(C9=C(O)C=CC=C9)=C8)=C7)CC6)C5)CC4.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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SMD-3040 TFA Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMD-3040SMD3040SMD 3040Ligands for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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