1. Stem Cell/Wnt TGF-beta/Smad
  2. PKA
  3. PKA Inhibitor Fragment (6-22) amide TFA

PKA Inhibitor Fragment (6-22) amide TFA  (Synonyms: PKI-(6-22)-amide TFA)

Cat. No.: HY-P1290A Purity: 99.77%
COA Handling Instructions

PKA Inhibitor Fragment (6-22) amide TFA is an inhibitor of cAMP-dependent protein kinase A (PKA), with a Ki of 2.8 nM. PKA Inhibitor Fragment (6-22) amide TFA can significantly reverse antinociceptive tolerance in mice.

For research use only. We do not sell to patients.

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PKA Inhibitor Fragment (6-22) amide TFA Chemical Structure

PKA Inhibitor Fragment (6-22) amide TFA Chemical Structure

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Based on 2 publication(s) in Google Scholar

Other Forms of PKA Inhibitor Fragment (6-22) amide TFA:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE PKA Inhibitor Fragment (6-22) amide TFA

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Description

PKA Inhibitor Fragment (6-22) amide TFA is an inhibitor of cAMP-dependent protein kinase A (PKA), with a Ki of 2.8 nM. PKA Inhibitor Fragment (6-22) amide TFA can significantly reverse antinociceptive tolerance in mice[1][2].

IC50 & Target[1]

PKA

2.8 nM (Ki)

Formula

C80H130N28O24.xC2HF3O2

Appearance

Solid

Color

White to off-white

Sequence Shortening

TYADFIASGRTGRRNAI-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.77%

References
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PKA Inhibitor Fragment (6-22) amide TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PKA Inhibitor Fragment (6-22) amide TFA
Cat. No.:
HY-P1290A
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