2. PI3K/Akt/mTOR
  3. Akt
  4. AKTide-2T TFA

AKTide-2T TFA is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.

For research use only. We do not sell to patients.

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AKTide-2T TFA Chemical Structure

AKTide-2T TFA Chemical Structure

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Other Forms of AKTide-2T TFA:

AKTide-2T TFA Related Antibodies

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Description

AKTide-2T TFA is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1].

In Vitro

AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AKTide-2T TFA Related Antibodies
Molecular Weight

1715.87 (free acid)

Formula

C74H114N28O20.xC2HF3O2
Sequence

Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala
Sequence Shortening

ARKRERTYSFGHHA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AKTide-2T TFA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKTide-2TAktPKBProtein kinase BAkt Substratehistone H2BAKTideinhibitory peptideInhibitorinhibitorinhibit

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