1. Cell Cycle/DNA Damage Apoptosis Metabolic Enzyme/Protease
  2. Survivin HSP
  3. Shepherdin (79-87) (TFA)

Shepherdin (79-87) TFA is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity.

For research use only. We do not sell to patients.

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Shepherdin (79-87) (TFA) Chemical Structure

Shepherdin (79-87) (TFA) Chemical Structure

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1 mg USD 50 In-stock
5 mg USD 75 In-stock
10 mg USD 120 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Shepherdin (79-87) TFA is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity[1].

Molecular Weight

1063.11

Formula

C43H65F3N12O14S

Appearance

Solid

Color

White to off-white

Sequence

Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu

Sequence Shortening

KHSSGCAFL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 70 mg/mL (65.84 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9406 mL 4.7032 mL 9.4064 mL
5 mM 0.1881 mL 0.9406 mL 1.8813 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.9406 mL 4.7032 mL 9.4064 mL 23.5159 mL
5 mM 0.1881 mL 0.9406 mL 1.8813 mL 4.7032 mL
10 mM 0.0941 mL 0.4703 mL 0.9406 mL 2.3516 mL
15 mM 0.0627 mL 0.3135 mL 0.6271 mL 1.5677 mL
20 mM 0.0470 mL 0.2352 mL 0.4703 mL 1.1758 mL
25 mM 0.0376 mL 0.1881 mL 0.3763 mL 0.9406 mL
30 mM 0.0314 mL 0.1568 mL 0.3135 mL 0.7839 mL
40 mM 0.0235 mL 0.1176 mL 0.2352 mL 0.5879 mL
50 mM 0.0188 mL 0.0941 mL 0.1881 mL 0.4703 mL
60 mM 0.0157 mL 0.0784 mL 0.1568 mL 0.3919 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Shepherdin (79-87) (TFA) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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