2. MAPK/ERK Pathway
  3. JNK
  4. JTP10-△-TATi TFA

JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor, with an IC50 of 92 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

JTP10-△-TATi TFA Chemical Structure

JTP10-△-TATi TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 80 In-stock
5 mg USD 220 In-stock
10 mg USD 350 In-stock
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Based on 1 publication(s) in Google Scholar

JTP10-△-TATi TFA Related Antibodies

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Description

JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor, with an IC50 of 92 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3[1].

IC50 & Target[1]

JNK2

92 nM (IC50)

JNK1

1.16 μM (IC50)

JNK3

1.2 μM (IC50)

In Vitro

JTP10-△-TATi TFA inhibits the migration of PyVMTjnk2+/+ cells and PyVMTjnk2-/- cells expressing GFP-JNK2α[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

JTP10-△-TATi TFA Related Antibodies
Molecular Weight

2833.28

Formula

C120H213F3N48O28
Appearance

Solid

Color

White to off-white

Sequence Shortening

Ac-PKRPTTLNLF-{Ahx}-RRRQRRKKRG-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 53.3 mg/mL (18.81 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3529 mL 1.7647 mL 3.5295 mL
5 mM 0.0706 mL 0.3529 mL 0.7059 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.3529 mL 1.7647 mL 3.5295 mL 8.8237 mL
5 mM 0.0706 mL 0.3529 mL 0.7059 mL 1.7647 mL
10 mM 0.0353 mL 0.1765 mL 0.3529 mL 0.8824 mL
15 mM 0.0235 mL 0.1176 mL 0.2353 mL 0.5882 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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JTP10-△-TATi TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JTP10-△-TATiJNKc-Jun N-terminal kinaseBreastcancerInhibitorinhibitorinhibit

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