1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. PD-1/PD-L1-IN 3 TFA

PD-1/PD-L1-IN 3 TFA 

Cat. No.: HY-103048A
Handling Instructions

PD-1/PD-L1-IN 3 TFA is a PD-1/PD-L1 interaction inhibitor extracted from patent WO2014151634A1, compound 1. PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PD-1/PD-L1-IN 3 TFA Chemical Structure

PD-1/PD-L1-IN 3 TFA Chemical Structure

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Description

PD-1/PD-L1-IN 3 TFA is a PD-1/PD-L1 interaction inhibitor extracted from patent WO2014151634A1, compound 1. PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM[1].

IC50 & Target

IC50: 9 nM (PD-1/PD-L1)[1]

Molecular Weight

1966.19

Formula

C₉₁H₁₂₇F₃N₂₄O₂₀S

Sequence

{Maa}{Phe}{Ala}{Asn}{Pro}{His}{Leu}{Sar}{Trp}{Ser}{Trp}{Nle}{Nle}{Arg}{Cys}{Gly} (Disulfide bridge: Maa1-Cys15)

Sequence Shortening

Maa-FANPHL-Sar-WSW-Nle-Nle-RCG (Disulfide bridge: Maa1-Cys15)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

PD-1/PD-L1-IN 3PD-1/PD-L1PD-1/Programmed death-ligand 1cancerinfectiousinteractionbindingregionssensitiveresistantInhibitorinhibitorinhibit

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Product name:
PD-1/PD-L1-IN 3 TFA
Cat. No.:
HY-103048A
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