Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA
Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) is a cleavable linker, that can be used to synthesize Antibody-Drug Conjugates (ADCs).
For research use only. We do not sell to patients.
- CAS No.: 2734877-83-7
- Formula: C44H51F3N3O15P
- Molecular Weight:949.86
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2734877-83-7
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Appearance Solid
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Molecular Weight 949.86
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Formula C44H51F3N3O15P
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Color White to off-white
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SMILES
NCC(N[C@@H](CCC(O)=O)C(NC1=CC(CC(C=C2)=CC=C2[C@H]3O[C@]4(C(COP(O)(O)=O)=O)[C@H](O3)C[C@@]5([H])[C@]6([H])CCC7=CC(C=C[C@]7(C)[C@@]6([H])[C@@H](O)C[C@@]54C)=O)=CC=C1)=O)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
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Data Sheet (242 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA Related Classifications
HY-400356 Related Classifications
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