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TNF-α (31-45), human TFA

13 Cited Publications
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Based on 13 publication(s) in Google Scholar

TNF-α (31-45), human TFA is a potent NF-kB pathway activator. TNF-αis a proinflammatory cytokine that induces necrosis or apoptosis. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis.

For research use only. We do not sell to patients.

  • Purity: 99.40%
  • Formula: C69H122N26O22.xC2HF3O2
  • Molecular Weight:1667.87 (free acid)
  • Storage:

    Sealed storage, away from moisture and light.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • TNF-α (31-45), human TFA Chemical Structure
    TNF-α (31-45), human TFA Chemical Structure
  • Experimental Validation Results for TNF-α (31-45), human TFA
  • Experimental Validation Results for TNF-α (31-45), human TFA
  • Experimental Validation Results for TNF-α (31-45), human TFA
  • Experimental Validation Results for TNF-α (31-45), human TFA
  • Experimental Validation Results for TNF-α (31-45), human TFA
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WBBio/Physico-chemical AssayRT-PCR
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All TNF Receptor Isoforms

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All NF-κB Isoforms

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  • TNF-α (31-45), human TFA Chemical Structure
    TNF-α (31-45), human TFA Chemical Structure
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    TNF-α (31-45), human TFA purchased from MedChemExpress. Usage Cited in: PLoS One. 2025 Apr 16;20(4):e0318311. [Abstract]

    Customer Validation
     TNF-α (31-45), human (100 ng/mL; 24 h). In vitro experimental validation was performed using Western blot.

  • 1/16

    TNF-α (31-45), human TFA purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2023 Dec 15:961:176193. [Abstract]

    Customer Validation
     TNF-α(31-45), human (10 ng/mL; 24 h). The LDH level of supernatant from TNF-α-stimulated hepatocytes.

  • 1/16

    TNF-α (31-45), human TFA purchased from MedChemExpress. Usage Cited in: Eur J Pharmacol. 2023 Dec 15:961:176193. [Abstract]

    Customer Validation
     TNF-α (31-45), human (10 ng/mL; 24 h). Immunoblotting of cleaved caspases 8 and 3 in TNF-α-stimulated hepatocytes. Blots were normalized to endogenous β-actin.

  • 1/16

    TNF-α (31-45), human TFA purchased from MedChemExpress. Usage Cited in: Biomedicines. 2023 Dec 15;11(12):3314. [Abstract]

    Customer Validation
     TNF-α (31-45), human (0.5-2 μg/L; 48 h). Effects of dose-elevated TNF-α on the protein levels of MATE1 and OCT2 in HK-2 cells.

  • 1/16

    TNF-α (31-45), human TFA purchased from MedChemExpress. Usage Cited in: Cytotechnology. 2021 Oct;73(5):727-743. [Abstract]

    Customer Validation
     TNF-α (31-45), human (0.5 ng/mL). The expression of miR-200b-3p in each group was detected by qRT-PCR.

  • TNF-α (31-45), human TFA