1. GPCR/G Protein
    Neuronal Signaling
  2. Orexin Receptor (OX Receptor)
  3. [Ala11,D-Leu15]-Orexin B(human) TFA

[Ala11,D-Leu15]-Orexin B(human) TFA 

Cat. No.: HY-P1340A
Handling Instructions

[Ala11,D-Leu15]-Orexin B(human) TFA is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) TFA shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

[Ala11,D-Leu15]-Orexin B(human) TFA Chemical Structure

[Ala11,D-Leu15]-Orexin B(human) TFA Chemical Structure

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Description

[Ala11,D-Leu15]-Orexin B(human) TFA is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) TFA shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 & Target

OX2

0.13 (EC50)

OX1

52 (EC50)

Molecular Weight

2971.28

Formula

C₁₂₂H₂₀₇F₃N₄₄O₃₇S

Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Sequence Shortening

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

[Ala11,D-Leu15]-Orexin B(human)Orexin Receptor (OX Receptor)Hypocretin ReceptorHCRT ReceptorL-alanineD-aminoacidselectivityneuropeptideInhibitorinhibitorinhibit

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[Ala11,D-Leu15]-Orexin B(human) TFA
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HY-P1340A
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