2. GPCR/G Protein Neuronal Signaling
  3. Orexin Receptor (OX Receptor)
  4. [Ala11,D-Leu15]-Orexin B(human)

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM).

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[Ala11,D-Leu15]-Orexin B(human)

[Ala11,D-Leu15]-Orexin B(human) Estructura química

No. CAS : 532932-99-3

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Based on 1 publication(s) in Google Scholar

Other Forms of [Ala11,D-Leu15]-Orexin B(human):

[Ala11,D-Leu15]-Orexin B(human) Related Antibodies

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OX2 Receptor OX1 Receptor

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Descripciòn

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 & Target[1]

OX2

0.13 nM (EC50)

OX1

52 nM (EC50)

Peso molecular

2857.26

Fòrmula

C120H206N44O35S
No. CAS
Appearance

Solid

Color

White to off-white

Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-{dLeu}-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening

RSGPPGLQGRAQRL-{dLeu}-QASGNHAAGILTM-NH2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

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Referencias
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[Ala11,D-Leu15]-Orexin B(human) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ala11,D-Leu15]-Orexin B(human)532932-99-3Orexin Receptor (OX Receptor)Hypocretin ReceptorHCRT ReceptorL-alanineD-aminoacidselectivityneuropeptideInhibitorinhibitorinhibit

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Nombre del producto:
[Ala11,D-Leu15]-Orexin B(human)
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HY-P1340
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