2. Apoptosis
  3. Bcl-2 Family
  4. PUMA BH3 TFA

PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.

For research use only. We do not sell to patients.

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PUMA BH3 TFA Chemical Structure

PUMA BH3 TFA Chemical Structure

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PUMA BH3 TFA Related Antibodies

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Description

PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM[1].

IC50 & Target[1]

Bak

26 nM (Kd)

In Vitro

PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 TFA binds Bak in the canonical BH3-binding groove, and activates Bak[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PUMA BH3 TFA Related Antibodies
Molecular Weight

2384.63 (free base)

Formula

C100H162N34O32S.xC2HF3O2
Sequence

Ac-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-NH2
Sequence Shortening

Ac-EQWAREIGAQLRRMADDLNA-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PUMA BH3 TFA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PUMA BH3PUMA BH 3PUMA BH-3Bcl-2 FamilyInhibitorinhibitorinhibit

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PUMA BH3 TFA
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HY-P1562A
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