PUMA BH3 TFA
PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.
For research use only. We do not sell to patients.
- Formula: C100H162N34O32S·xC2HF3O2
- Molecular Weight:2384.63 (free base)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Bak 26 nM (Kd) |
PUMA BH3 TFA is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 TFA binds Bak in the canonical BH3-binding groove, and activates Bak[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 2384.63 (free base)
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Formula C100H162N34O32S·xC2HF3O2
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Sequence
Ac-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-NH2
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Sequence Shortening
Ac-EQWAREIGAQLRRMADDLNA-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)