1. Apoptosis
  2. Bcl-2 Family

PUMA BH3 

Cat. No.: HY-P1562
Handling Instructions

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. Sequence: Glu-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-Gln-Tyr-Glu-Arg;EEQWAREIGAQLRRMADDLNAQYER.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

PUMA BH3 Chemical Structure

PUMA BH3 Chemical Structure

Size Price Stock
1 mg USD 150 Get quote
5 mg USD 350 Get quote
10 mg USD 550 Get quote

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. Sequence: Glu-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-Gln-Tyr-Glu-Arg;EEQWAREIGAQLRRMADDLNAQYER.

IC50 & Target

Bak

26 nM (Kd)

In Vitro

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3279 mL 1.6397 mL 3.2794 mL
5 mM 0.0656 mL 0.3279 mL 0.6559 mL
10 mM 0.0328 mL 0.1640 mL 0.3279 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

3049.30

Formula

C₁₂₈H₂₀₂N₄₂O₄₃S

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PUMA BH3
Cat. No.:
HY-P1562
Quantity:

PUMA BH3

Cat. No.: HY-P1562