PAMP-12(human, porcine) TFA

Cat. No.: HY-P2198A: Ficha de datos Instrucciones de manejo
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PAMP-12(human, porcine) TFA is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control.

Para uso exclusivo en investigación. No vendemos a pacientes.

PAMP-12(human, porcine) TFA Estructura química

Tamaño		Stock
MOQ		Minimum order quantity
50 mg		Obtener un presupuesto
100 mg		Obtener un presupuesto
250 mg		Obtener un presupuesto
Other size		Obtener un presupuesto

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This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of PAMP-12(human, porcine) TFA:

PAMP-12(human, porcine)

Other Forms of PAMP-12(human, porcine) TFA:

PAMP-12(human, porcine) In-stock

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Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

In Vitro

PAMP-12 (human, porcine) is the PAMP[9-20] with a C-terminal amide structure. Intravenous injections of PAMP-12 in anesthetized rats show a significant hypotensive effect in a dose-dependent fashion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

1732.95

Fòrmula

C₇₉H₁₂₀F₃N₂₅O₁₆

Sequence

Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2

Sequence Shortening

FRKKWNKWALSR-NH2

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvente y solubilidad

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. K Kuwasako, et al. Purification and Characterization of PAMP-12 (PAMP[9-20]) in Porcine Adrenal Medulla as a Major Endogenous Biologically Active Peptide. FEBS Lett. 1997 Sep 1;414(1):105-10. [Content Brief]