1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. ACTH (1-14) (TFA)

ACTH (1-14) (TFA)  (Synonyms: Adrenocorticotropic Hormone Fragment 1-14 TFA)

Cat. No.: HY-P1582A Purity: 98.02%
COA Handling Instructions

ACTH (1-14) (TFA) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

ACTH (1-14) (TFA) Chemical Structure

ACTH (1-14) (TFA) Chemical Structure

Size Price Stock Quantity
1 mg USD 80 In-stock
5 mg USD 180 In-stock
10 mg USD 280 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of ACTH (1-14) (TFA):

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Description

ACTH (1-14) (TFA) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production[1].

In Vitro

Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1794.90

Formula

C79H110F3N21O22S

Appearance

Solid

Color

White to off-white

Sequence

Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly

Sequence Shortening

SYSMEHFRWGKPVG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (55.71 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5571 mL 2.7857 mL 5.5713 mL
5 mM 0.1114 mL 0.5571 mL 1.1143 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (13.93 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5571 mL 2.7857 mL 5.5713 mL 13.9284 mL
5 mM 0.1114 mL 0.5571 mL 1.1143 mL 2.7857 mL
10 mM 0.0557 mL 0.2786 mL 0.5571 mL 1.3928 mL
15 mM 0.0371 mL 0.1857 mL 0.3714 mL 0.9286 mL
20 mM 0.0279 mL 0.1393 mL 0.2786 mL 0.6964 mL
25 mM 0.0223 mL 0.1114 mL 0.2229 mL 0.5571 mL
30 mM 0.0186 mL 0.0929 mL 0.1857 mL 0.4643 mL
40 mM 0.0139 mL 0.0696 mL 0.1393 mL 0.3482 mL
50 mM 0.0111 mL 0.0557 mL 0.1114 mL 0.2786 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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ACTH (1-14) (TFA) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ACTH (1-14) (TFA)
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