1. GPCR/G Protein
  2. Angiotensin Receptor
  3. H-Val-Pro-Pro-OH TFA

H-Val-Pro-Pro-OH TFA 

Cat. No.: HY-114161A Purity: >98.0%
Handling Instructions

H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

H-Val-Pro-Pro-OH TFA Chemical Structure

H-Val-Pro-Pro-OH TFA Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 70 In-stock
Estimated Time of Arrival: December 31
25 mg USD 120 In-stock
Estimated Time of Arrival: December 31
50 mg USD 190 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of H-Val-Pro-Pro-OH TFA:

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM.

IC50 & Target

IC50: 9 μM (ACE)[1].

In Vitro

H-Val-Pro-Pro-OH (TFA), a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM[1]. H-Val-Pro-Pro-OH (TFA) could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH (TFA) also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH (TFA) further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes[2].

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 160 mg/mL (376.12 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3507 mL 11.7536 mL 23.5073 mL
5 mM 0.4701 mL 2.3507 mL 4.7015 mL
10 mM 0.2351 mL 1.1754 mL 2.3507 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

425.40

Formula

C₁₇H₂₆F₃N₃O₆

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
H-Val-Pro-Pro-OH TFA
Cat. No.:
HY-114161A
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H-Val-Pro-Pro-OH TFA

Cat. No.: HY-114161A