1. PI3K/Akt/mTOR
    Stem Cell/Wnt
  2. GSK-3
  3. 2B-(SP) (TFA)

2B-(SP) (TFA) 

Cat. No.: HY-P1114A
Handling Instructions

2B-(SP) TFA is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) TFA is readily phosphorylated by both the α and β isoforms of GSK-3.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

2B-(SP) (TFA) Chemical Structure

2B-(SP) (TFA) Chemical Structure

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Description

2B-(SP) TFA is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) TFA is readily phosphorylated by both the α and β isoforms of GSK-3[1].

IC50 & Target[1]

GSK-3α

 

GSK-3β

 

Molecular Weight

1949.89

Formula

C₇₃H₁₂₄F₃N₂₆O₃₁P

Sequence

Arg-Arg-Ala-Ala-Glu-Glu-Leu-Asp-Ser-Arg-Ala-Gly-{Ser(PO3H2)}-Pro-Gln-Leu

Sequence Shortening

RRAAEELDSRAG-{Ser(PO3H2)}-PQL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

2B-(SP) (TFA)GSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3phosphorylatedeIF2B-basedGSK-3βInhibitorinhibitorinhibit

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2B-(SP) (TFA)
Cat. No.:
HY-P1114A
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