1. Neuronal Signaling
  2. CaMK

Autocamtide-2-related inhibitory peptide TFA 

Cat. No.: HY-P0214A Purity: 98.48%
Handling Instructions

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Autocamtide-2-related inhibitory peptide TFA Chemical Structure

Autocamtide-2-related inhibitory peptide TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 220 In-stock
Estimated Time of Arrival: December 31
5 mg USD 890 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

IC50 & Target

IC50: 40 nM (CaMKII)[1].

In Vitro

It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6204 mL 3.1022 mL 6.2044 mL
5 mM 0.1241 mL 0.6204 mL 1.2409 mL
10 mM 0.0620 mL 0.3102 mL 0.6204 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1611.76

Formula

C₆₆H₁₂₆N₂₂O₂₁F₃

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Autocamtide-2-related inhibitory peptide TFA
Cat. No.:
HY-P0214A
Quantity:

Autocamtide-2-related inhibitory peptide TFA

Cat. No.: HY-P0214A