1. Neuronal Signaling
    Autophagy
  2. CaMK
    Autophagy
  3. Autocamtide-2-related inhibitory peptide (TFA)

Autocamtide-2-related inhibitory peptide (TFA) 

Cat. No.: HY-P0214A Purity: 98.48%
Handling Instructions

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Autocamtide-2-related inhibitory peptide (TFA) Chemical Structure

Autocamtide-2-related inhibitory peptide (TFA) Chemical Structure

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1 mg USD 220 In-stock
Estimated Time of Arrival: December 31
5 mg USD 890 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

IC50 & Target

IC50: 40 nM (CaMKII)[1].

In Vitro

It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used[1].

Molecular Weight

1611.76

Formula

C₆₆H₁₂₆N₂₂O₂₁F₃

Sequence

Lys-Lys-Ala-Lru-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu

Sequence Shortening

KKALRRQEAVDAL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

Autocamtide-2-related inhibitory peptide (TFA)CaMKAutophagyCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesInhibitorinhibitorinhibit

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Autocamtide-2-related inhibitory peptide (TFA)
Cat. No.:
HY-P0214A
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