Autocamtide-2-related inhibitory peptide
Based on 1 Customer Validation
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
For research use only. We do not sell to patients.
- CAS No.: 167114-91-2
- Formula: C64H116N22O19
- Molecular Weight:1497.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Autocamtide-2-related inhibitory peptide
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Biological Activity
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CaMK II |
It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu
KKALRRQEAVDAL
Chemical Information
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CAS No. 167114-91-2
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Molecular Weight 1497.74
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Formula C64H116N22O19
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection. [Abstract]2021 Jun 10;12(1):3519. PMID: 34112781 -
Biomed Pharmacother
PIEZO1 as a new target for hyperglycemic stress-induced neuropathic injury: The potential therapeutic role of bezafibrate. [Abstract]2024 Jul:176:116837. PMID: 38815290
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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