1. Neuronal Signaling
  2. CaMK
  3. KN-92 phosphate

KN-92 phosphate 

Cat. No.: HY-15517A Purity: 99.94%
Handling Instructions

KN-92 phosphate is an inactive derivative of KN-93.

For research use only. We do not sell to patients.

KN-92 phosphate Chemical Structure

KN-92 phosphate Chemical Structure

CAS No. : 1135280-28-2

Size Price Stock Quantity
2 mg USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 220 In-stock
Estimated Time of Arrival: December 31
10 mg USD 330 In-stock
Estimated Time of Arrival: December 31
50 mg USD 980 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of KN-92 phosphate:

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Publications Citing Use of MCE KN-92 phosphate

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KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). IC50 value: Target: KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell.

Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (180.19 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8019 mL 9.0093 mL 18.0187 mL
5 mM 0.3604 mL 1.8019 mL 3.6037 mL
10 mM 0.1802 mL 0.9009 mL 1.8019 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.50 mM); Clear solution

*All of the co-solvents are provided by MCE.

Purity: 99.94%

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2


KN-92KN92KN 92CaMKAutophagyCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesInhibitorinhibitorinhibit

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