2. JAK/STAT Signaling
    Stem Cell/Wnt
  3. STAT
  4. CMD178 TFA

CMD178 TFA 

Cat. No.: HY-P1453A Purity: 99.83%
COA Handling Instructions

CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CMD178 TFA Chemical Structure

CMD178 TFA Chemical Structure

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 1379 In-stock
Solid
1 mg USD 350 In-stock
5 mg USD 650 In-stock
10 mg USD 1050 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of CMD178 TFA:

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  • References

  • Customer Review

Description

CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].

In Vitro

CMD178 TFA (100 μM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].
CMD178 TFA (100 μM) inhibits the development of Treg cells induced by IL2/sIL-2Rα signaling[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

964.05

Appearance

Solid

Formula

C9H8F5KO3Y
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro: 

H2O : 2.5 mg/mL (2.59 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0373 mL 5.1865 mL 10.3729 mL
5 mM --- --- ---
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CMD178CMD 178CMD-178STATlead peptidecomputationally designed peptidesFoxp3soluble IL-2RaSTAT5Treg cellsInhibitorinhibitorinhibit

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CMD178 TFA
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